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Zyclara Uses

Zyclara is a prescription medicine specifically approved to treat actinic keratosis lesions that occur on the face or bald/balding scalp in adults. The medicated skin cream is also approved for treating genital warts or perianal warts in people age 12 and older. Some off-label Zyclara uses include treating various types of skin cancer and other types of warts.

What Is Zyclara Used For?

Zyclara® (imiquimod cream) is a prescription skin cream that is used to treat the following conditions:
  • Actinic keratosis (AK), also known as solar keratosis, of the face or bald/balding scalp in adults with normal immune systems
  • External genital warts and perianal warts in people age 12 and older.

Zyclara Use for Actinic Keratosis

Actinic keratosis lesions are scaly bumps or patches on the surface if the skin due to sun damage. They range in size and color. Although actinic keratoses may be unsightly, the more serious concern is that some lesions may progress to a type of skin cancer known as squamous cell carcinoma.
Treatment for AK may include:
  • Freezing (cryosurgery)
  • Laser surgery
  • Medications.
Although actinic keratosis lesions can appear on any part of the skin that is exposed to the sun, Zyclara is approved only for use on the face or a bald (or balding) scalp.

Using Zyclara for Genital or Perianal Warts

Genital warts are a common and bothersome problem. Symptoms include skin-colored growths, much like warts on other parts of the body. They are usually not painful. Male genital warts usually occur on the penis, and female genital warts can occur outside (on the vulva) or inside (on the vagina or cervix). Genital warts can also occur on the scrotum or anus. They are caused by the human papillomavirus (HPV).
HPV warts are common and spread easily through sexual contact. Condoms do not fully protect against HPV, as they often do not cover all of the warts.
Treatments for genital warts include several ways to remove the warts, such as with chemical treatments or freezing. Talk to your healthcare provider about genital warts treatment. Over-the-counter (OTC) products should never be used for the treatment of genital warts. There is no definite way to cure genital warts, and they may disappear and return on their own.
Zyclara may help your body get rid of genital or perianal warts. Studies have shown that more people using Zyclara had a complete disappearance of their warts, compared to people using a cream that did not contain any active ingredients (a placebo).
The lower strength of Zyclara (2.5%), which has been approved but is not yet commercially available, is not approved for this use. Only the 3.75% strength of Zyclara is approved for treating warts. Both strengths are approved for actinic keratosis treatment.

Zyclara Medication Information

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