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Xolegel and Breastfeeding

The active ingredient in Xolegel (ketoconazole) is known to pass through breast milk when the drug is taken by mouth. However, when applied to the skin, only a small amount of the active ingredient is expected to be absorbed into the bloodstream. Although the American Academy of Pediatrics considers Xolegel compatible with breastfeeding, make sure to talk to your healthcare provider about the potential risks.

Can Breastfeeding Women Use Xolegel?

Xolegel® (ketoconazole gel) is a skin medication used to treat seborrhea. At this time, it is unknown if Xolegel is safe for use while nursing. Therefore, if you are breastfeeding or plan to start, talk to your healthcare provider before using Xolegel.

More Information on Xolegel and Breastfeeding

Ketoconazole (the active ingredient in Xolegel) passes through breast milk when it is taken by mouth. However, when applied to the skin, Xolegel is absorbed in such low amounts that it seems unlikely for the drug to be passed through breast milk in any significant amount.
Direct skin-to-skin contact (for areas where the gel has been applied) should be avoided, to avoid exposing the baby to the medication by skin transfer. Also, avoid applying Xolegel near or on the nipple; if this is not possible, make sure to completely remove the medication before the baby nurses.
The American Academy of Pediatrics (AAP) considers ketoconazole compatible with breastfeeding.

Talking With Your Healthcare Provider

You should discuss breastfeeding and Xolegel use with your healthcare provider. Each woman's situation is different, and you and your healthcare provider understand your situation best. After considering what you want and expect, as well as your current health situation, the two of you can make a shared decision that is right for you.
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Xolegel Medication Information

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