Skin Home > Vorinostat

Vorinostat is licensed for the treatment of cutaneous T-cell lymphoma when the cancer has not improved, gotten worse, or comes back after at least two other medications have been tried unsuccessfully. This chemotherapy drug works by disrupting the multiplication process of the cancer cells. Available in the form of a capsule, vorinostat is usually taken once a day.

What Is Vorinostat?

Vorinostat (Zolinza®) is a prescription medication approved to treat cutaneous T-cell lymphoma, a type of cancer of the immune system that affects the skin. It is approved for use when the cancer has not improved or has gotten worse, or when the cancer has come back after treatment with at least two other medications.
(Click What Is Vorinostat Used For? for more information on this topic, including possible off-label uses.)

Are There Side Effects?

Just like any chemotherapy medicine, vorinostat can cause side effects, some of which can be quite significant. In fact, the majority of people who use this drug will experience some type of adverse reaction during treatment. Talk with your healthcare provider about ways to prevent or treat certain side effects of this medicine.
Common side effects of vorinostat include but are not limited to:
  • Fatigue
  • Diarrhea
  • Nausea
  • An abnormal taste in the mouth
  • Loss of appetite.
(Click Vorinostat Side Effects to learn more, including potentially serious side effects you should report immediately to your healthcare provider.)
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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