Skin Home > Picato Side Effects

During clinical studies on Picato, the most common side effects were skin reactions, such as redness, scaling, and itching. In fact, most people who use this medicated skin gel will develop some type of skin reaction. Fortunately, these reactions tend to be minor and treated easily. However, call your healthcare provider immediately if you develop more serious problems like intolerable skin reactions or difficulty breathing.

An Introduction to Picato Side Effects

Just like any medicine, Picato® (ingenol mebutate) can cause side effects. However, not everyone who uses the medication will have problems. In fact, most people tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider.
Although almost all people using this medication will develop some sort of skin reaction to the product, most reactions such as these are minor.
(This article covers many, but not all, of the possible side effects with Picato. Your healthcare provider can discuss a more complete list with you.)

Common Side Effects of Picato

Picato has been studied extensively in clinical trials. In these studies, the side effects that occurred in a group of people using the drug were documented and compared to those that occurred in another group of people using a gel that did not contain any active ingredients (a placebo). As a result, it was possible to see what side effects occurred, how often they appeared, and how they compared to the placebo.
In these studies, the most common Picato side effects were skin reactions, including but not limited to:
  • Redness -- in up to 94 percent of people
  • Flaking or scaling -- up to 90 percent
  • Crusting -- up to 80 percent
  • Swelling -- up to 79 percent
  • Blistering (including fluid-filled blisters) -- up to 56 percent
  • Erosion of the skin -- up to 32 percent
  • Pain -- up to 15 percent
  • Itching -- up to 8 percent.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
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