Skin Home > Treatment Instructions for OnabotulinumtoxinA

When and How Do I Take It?

General considerations to keep in mind when taking onabotulinumtoxinA include the following:
  • The drug comes in injectable form. It is injected directly into the muscles that are causing the problems. When treating severe sweating, onabotulinumtoxinA is injected directly into the underarm.
  • When treating misaligned eyes (strabismus), special techniques -- sometimes using the electrical signals from the muscles -- must be used to make sure that the injections are given in the right place.


  • For injection into the bladder, you might be sedated or put under general anesthesia, depending on several factors. 


  • Your healthcare provider may choose to use an anesthetic cream to numb your skin before the injection, but this is not necessary. If you are worried about pain, ask your healthcare provider about using an anesthetic cream.
  • The effects of onabotulinumtoxinA are not permanent. You will need to receive injections periodically in order to maintain the effects.

Dosing Information

The dose of onabotulinumtoxinA your healthcare provider recommends will vary, depending on a number of factors, including:
  • The condition being treated
  • How you respond to the injections
  • Other medical conditions you may have
  • Other medications you may be currently taking.
As always, do not adjust your dose unless your healthcare provider specifically tells you to do so.
(Click OnabotulinumtoxinA Dosage for more information.)

OnabotulinumtoxinA Drug Interactions

This medication can interact with a number of other medicines (see Drug Interactions With OnabotulinumtoxinA).
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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