Skin Home > OnabotulinumtoxinA Dosage

The standard dosage of onabotulinumtoxinA for severe underarm sweating is 50 units per underarm, given in several small injections. However, many factors will affect the actual amount your healthcare provider recommends, including the condition being treated, how you respond to the drug, and if other medical conditions are present. You will need to receive repeat injections periodically to maintain the desired results.

An Introduction to Dosing With OnabotulinumtoxinA

The dose of onabotulinumtoxinA (Botox®) your healthcare provider recommends will vary, depending on a number of factors, including:
  • The condition being treated
  • How you respond to onabotulinumtoxinA
  • Other medical conditions you may have
  • Other medications you may be currently taking.
As always, do not adjust this amount unless your healthcare provider specifically tells you to do so.

OnabotulinumtoxinA Dosage for Wrinkles

OnabotulinumtoxinA is approved to treat "frown lines" between the eyebrows. The recommended dose to treat these kinds of wrinkles is five injections of onabotulinumtoxinA, each containing 0.1 mL (four units) of the drug, in specific areas above and between the eyebrows.
OnabotulinumtoxinA is also approved to treat crow's feet. For these wrinkles, the usual pattern is three injections (0.1 mL, or four units, each) on each eye, for a total of 24 units.

Dosing for Head and Neck Spasms

The amount of onabotulinumtoxinA used for head and neck spasms (known medically as cervical dystonia) varies from person to person, and is based on the characteristics of your spasms and how you respond to this medication. There is no standard recommended dosage for this use.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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