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Fluocinonide is a steroid used to treat inflammation and itching caused by eczema, psoriasis, and other skin conditions. It comes in a variety of forms, including a gel, topical solution, ointment, and cream. Typically, it is applied between one and four times a day. The most commonly reported side effects include itching, burning, and dryness.

What Is Fluocinonide?

Fluocinonide (Lidex®, Vanos®) is a prescription skin medication. It comes in the form of an ointment, gel, topical solution, or cream. Fluocinonide belongs to a group of medications known as topical steroids and is used to treat inflammation and itching due to a wide variety of skin conditions, such as eczema, psoriasis, dermatitis, and allergic reactions.
(Click What Is Fluocinonide Used For? for more information on this topic, including possible off-label uses.)

Are There Side Effects?

As with any medicine, fluocinonide may cause side effects. However, not everyone who uses the drug will experience problems. In fact, most people tolerate it quite well.
If side effects do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider. Serious reactions are less common.
The most common side effects of this medication include:
  • Headache
  • Burning
  • Irritation
  • Itching
  • Dryness.
(Click Fluocinonide Side Effects to learn more, including potentially serious side effects you should report immediately to your healthcare provider.)
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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