Skin Home > Fluocinolone Oil

A healthcare provider may prescribe fluocinolone oil to treat scalp psoriasis or atopic dermatitis. This medication is a type of steroid that works by reducing inflammation and suppressing the immune system. This oil is applied to the affected areas of the skin one to three times a day. Some of the common side effects may include dryness, irritation, and itching of the skin.

What Is Fluocinolone Oil?

Fluocinolone oil (Derma-Smoothe/FS®) is a prescription medication that belongs to a group of drugs known as topical steroids. It contains fluocinolone acetonide, a potent corticosteroid.
Fluocinolone scalp oil is approved to treat scalp psoriasis in adults. The body oil is approved to treat atopic dermatitis (a type of eczema) in children and adults. Fluocinolone oil is a topical medicine, which means it is applied directly on the skin.
(Click What Is Fluocinolone Oil Used For? for more information on this topic, including possible off-label uses.)

Are There Side Effects?

Just like any medicine, fluocinolone oil can cause side effects. However, not everyone who uses the medicine will have problems. In fact, most people tolerate it quite well.
If side effects do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider. Serious side effects are less common.
Some of the most common fluocinolone oil side effects include but are not limited to:
  • Burning
  • Itching
  • Irritation
  • Dryness.
(Click Fluocinolone Oil Side Effects to learn more, including potentially serious side effects you should report immediately to your healthcare provider.)
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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