Skin Home > Diflorasone Diacetate

Diflorasone diacetate is a topical prescription drug used to treat eczema, dermatitis, and a variety of other skin conditions. It comes in the form of a regular cream, an emollient cream, and an ointment, and is typically applied to the affected areas one to three times a day. Side effects are possible and may include burning, irritation, and dryness.

What Is Diflorasone Diacetate?

Diflorasone diacetate is a prescription skin medication. This is a topical steroid that is used to treat a wide variety of skin conditions, such as eczema, psoriasis, dermatitis, and allergic reactions. It comes in the form of a cream, an ointment, and an emollient cream (emollient creams are more moisturizing, compared to regular creams, while still being nongreasy).
The emollient cream is sold under the brand name ApexiCon® E Cream. The regular ointment and cream were originally sold under various brand names, but are currently available only in generic form.
(Click Diflorasone Diacetate Uses for more information on this topic, including possible off-label uses.)

Who Makes Diflorasone Diacetate?

Brand-name ApexiCon E Cream is made by PharmaDerm. Generic diflorasone diacetate products are made by various manufacturers, such as E. Fougera & Co. and Taro Pharmaceuticals.

How Does It Work?

Diflorasone diacetate is part of a group of medications known as glucocorticoids. Glucocorticoids are a type of corticosteroid, or "steroid" for short. Although glucocorticoids have numerous effects in the body, they are used mostly for their anti-inflammatory or immune-suppressing properties. Diflorasone diacetate works for most conditions by decreasing inflammation or suppressing an overactive immune system.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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