Adults who have Hodgkin's disease or malignant melanoma (a type of skin cancer) may receive dacarbazine (DTIC-Dome®). This prescription medication is given as an injection into a vein (by IV). It is usually given once a day for 5 to 10 days, followed by a break in treatment. There are two strengths of dacarbazine available:
Dacarbazine 100 mg
Dacarbazine 200 mg.
The specific dosage of dacarbazine your healthcare provider prescribes will depend on your weight, the reason you are using the drug, and various other factors. Some of the possible side effects of this drug include nausea, vomiting, and loss of appetite.
(For more details, click Dacarbazine. This resource takes a closer look at this drug, including dosing instructions and safety precautions to be aware of before beginning treatment.)
Written by/reviewed by: Kristi Monson, PharmD;Arthur Schoenstadt, MD
Food and Drug Administration, Center for Drug Evaluation and Research. Electronic orange book: approved drug products with therapeutic equivalence evaluations. FDA Web site. Available at: http://www.fda.gov/cder/ob/. Accessed September 13, 2012.
Briggs GG, Freeman RK, Yaffe SJ. Drugs in Pregnancy and Lactation. 8th ed. Philadelphia (PA): Lippincott Williams & Wilkins;2008.
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