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Precautions and Warnings With IncobotulinumtoxinA

People who receive incobotulinumtoxinA should be aware that this product could spread to other parts of the body, potentially causing serious problems. Also, this medicine may not be safe for people who have difficulty swallowing or certain neuromuscular diseases. Other warnings and precautions with incobotulinumtoxinA apply to women who are pregnant or breastfeeding.

What Should I Tell My Healthcare Provider Before Receiving IncobotulinumtoxinA?

You should talk with your healthcare provider before receiving incobotulinumtoxinA (Xeomin®) if you have:
  • An infection near the site where you would receive the injections
  • Difficulty swallowing
  • Neuromuscular disease, such as:
Also, let your healthcare provider know if you are:
  • Pregnant or thinking of becoming pregnant
  • Breastfeeding.
You should also tell your healthcare provider about all other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.

Specific IncobotulinumtoxinA Precautions and Warnings

Some warnings and precautions to be aware of prior to receiving this medication include the following:
  • In rare cases, incobotulinumtoxinA can spread from the site of the injection to distant parts of the body, potentially causing serious problems. This is most likely to occur if incobotulinumtoxinA is used to treat spasticity in children. It should be noted that incobotulinumtoxinA is not approved for use in children.
  • IncobotulinumtoxinA is quite similar to but not exactly the same as Botox® or Dysport®. The dosage of incobotulinumtoxinA cannot be compared or converted to a Botox dosage or Dysport dosage.
  • The medication can cause allergic reactions. Contact your healthcare provider right away if you develop any signs of an allergic reaction, such as:
    • An unexplained rash
    • Itching
    • Wheezing
    • Swelling
    • Difficulty breathing.
  • IncobotulinumtoxinA can cause difficulty swallowing, which may cause serious problems. This is more likely if you already have swallowing problems or if you have a neuromuscular disease.
  • This product contains albumin, a human protein. Theoretically, viruses or infectious proteins may be transmitted through albumin. However, there have never been any cases of this reported with an albumin product.
  • Sometimes, the medication can decrease your blinking reflex, especially if it is used near the eyes. This can dry out your eyes, increasing your risk for corneal abrasion or other eye problems. If your eyes seem to be dry, let your healthcare provider know right away.
  • Sometimes, incobotulinumtoxinA injections in the area near the eyes can cause vision changes. These changes are usually temporary.
  • IncobotulinumtoxinA is a pregnancy Category C medication. This means that it may not be safe for use during pregnancy, although the full risks are currently unknown (see Xeomin and Pregnancy).
  • It is not known if incobotulinumtoxinA passes through breast milk. Therefore, if you are breastfeeding or plan to start, discuss this with your healthcare provider prior to receiving the drug (see Xeomin and Breastfeeding).
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IncobotulinumtoxinA Drug Information

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