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Fluocinonide Side Effects

When used as directed, side effects are unlikely with fluocinonide. However, as with any medication, reactions are possible and may include irritation, itching, and dryness. Long-term side effects include diabetes, weight gain, and osteoporosis. If you develop any problems while using this drug, or if something "just doesn't seem right," talk to your healthcare provider.

An Introduction to Fluocinonide Side Effects

Just like any medicine, side effects are possible with fluocinonide (Lidex®, Vanos®). However, not everyone who uses the medication will experience problems. In fact, most people tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider.
(This article covers many, but not all, of the possible side effects with fluocinonide. Your healthcare provider can discuss a more complete list with you.)

Serious Side Effects of Fluocinonide

Some side effects of steroids such as fluocinonide are potentially serious and should be reported immediately to your healthcare provider. These include but are not limited to:
  • High blood pressure (hypertension)
  • High blood sugar (hyperglycemia) or diabetes
  • Infections
  • Ruptured tendons
  • Psychotic reactions, such as hallucinations or extreme aggression
  • Glaucoma
  • Severe fluid retention
  • Signs of an allergic reaction, including unexplained rash, hives, itching, and unexplained swelling.
In general, these serious reactions are extremely unlikely to occur when fluocinonide is used as directed for a short time. Applying too much over too large an area, for too long, may increase the risk of serious side effects.

Fluocinonide Drug Information

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