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Side Effects of Diclofenac Gel

With diclofenac gel, the most common side effects are skin reactions at the application site. These reactions include redness, dryness, numbness, and peeling skin. In most cases, side effects of this product are mild and either do not require treatment or can be treated easily. However, certain side effects are potentially serious and require immediate medical attention, including chest pain, slurred speech, or difficulty breathing.

An Introduction to Diclofenac Gel Side Effects

As with any medicine, side effects are possible with diclofenac gel (Solaraze® Gel, Voltaren® Gel). However, not everyone who takes the medication will experience side effects. In fact, most people tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or can easily be treated by you or your healthcare provider.
(This article covers many, but not all, of the possible side effects with Diclofenac Gel. Your healthcare provider can discuss a more complete list of Diclofenac Gel side effects with you.)

Serious Side Effects Seen With Diclofenac Gel

Diclofenac gel is a nonsteroidal anti-inflammatory medication (NSAID). As such, it can cause certain serious side effects that you should report to your healthcare provider. These include, but are not limited to:


    • Chest pain
    • Shortness of breath or other breathing difficulties
    • Pain in the shoulder, arm, or jaw



    • Slurred speech
    • Weakness on one side of the face or body
    • Confusion


  • Signs of bleeding of the digestive tract, such as dark, tarry stools or bloody vomit
  • Signs of liver problems, such as yellow eyes or skin (jaundice)
  • Rapid weight gain, water retention, or unusual swelling of the arms, legs, hands, or feet
  • Signs of an allergic reaction, including:


    • An unexplained rash
    • Hives
    • Itching
    • Unexplained swelling of the mouth or throat
    • Wheezing or difficulty breathing or swallowing.


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