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Cordran SP Cream and Pregnancy

When steroids such as Cordran SP Cream (flurandrenolide cream) were studied in pregnant animals, the drug increased the risk for problems such as birth defects and reduced survival rates. It is unknown if these problems would also occur in humans, but it is probably best to avoid using this medicine over a large area for extended periods.

Can Pregnant Women Use Cordran SP Cream?

Cordran® SP Cream (flurandrenolide cream) is a prescription topical steroid approved for treating a variety of different skin conditions. As is common with many medications, it is unclear if the drug is safe for use during pregnancy. In general, steroids should be used only if necessary, at the lowest effective dose, and for the shortest possible time during pregnancy.

What Is Pregnancy Category C?

The U.S. Food and Drug Administration (FDA) uses a category system to classify the possible risks to a fetus when a specific medicine is taken during pregnancy. Pregnancy Category C is given to medicines that have not been studied in pregnant humans but do appear to cause harm to the fetus in animal studies.
In addition, medicines that have not been studied in any pregnant women or animals are automatically given a pregnancy Category C rating.
Cordran SP Cream is a steroid. Animal studies have shown that steroids may increase the risk of birth defects, such as cleft palate, and may cause other problems, such as poor fetal growth or decreased survival. In animal studies, flurandrenolide cream (the active ingredient in Cordran SP Cream) appeared to increase the risk of poor fetal growth, miscarriages, and fetal malformations.
Similar problems might also occur in humans, although the risk is probably smaller with topical steroids that are applied to the skin, like Cordran SP Cream.
While short-term use (a few days) of Cordran SP Cream applied to a small area of the body is probably not likely to cause problems (although this is not known for sure), extended use or use over a large area of the body should generally be avoided during pregnancy if possible. In some cases, the benefits to the mother might outweigh the possible risks to the fetus.
Pregnancy and Pain

Cordran SP Cream Medication Information

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