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Clobex Side Effects

Most people who use Clobex do not experience problems. However, as with any medication, side effects are possible. Clobex has been reported to cause reactions such as headache, spider veins, and a burning sensation at the application site in clinical trials. Serious side effects -- including glaucoma or extreme aggression -- are also possible, but these are more likely when the drug has been used improperly.

An Introduction to Clobex Side Effects

As with any medicine, side effects are possible with Clobex® (clobetasol propionate). However, not everyone who uses the medication will experience problems. In fact, most people tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider.
(This article covers many, but not all, of the possible side effects with Clobex. Your healthcare provider can discuss a more complete list with you.)

Common Side Effects of Clobex

Clobex has been studied thoroughly in clinical trials. In these studies, one group of people received Clobex, while another group was given a placebo (a similar product with no active ingredients). As a result, it was possible to see what side effects occurred, how often they appeared, and how they compared to the placebo.
The reported side effects vary, depending on the particular form of Clobex (shampoo, lotion, or spray). In clinical trials, the most common reactions to Clobex shampoo included:
  • Headache -- up to 1.8 percent of people
  • Skin discomfort -- up to 4.7 percent.
For Clobex lotion, the most commonly reported side effects included:
  • Weakening and thinning of the skin -- in up to 4.2 percent of people
  • Spider veins -- up to 3.2 percent
  • Skin discomfort -- up to 1.3 percent
  • Dry skin -- up to 1 percent.
In studies, the most common reactions to the spray included but were not limited to:
  • Burning sensation at the application site -- in up to 40 percent of people
  • Upper respiratory tract infection (such as the common cold) -- up to 8 percent
  • Itching at the application site -- up to 3 percent
  • Asteatotic eczema (a type of eczema that involves very dry skin that appears cracked in an unusual pattern) -- up to 2 percent
  • Dry skin -- up to 2 percent.
In general, side effects are more common when a dressing, such as a bandage, is used to cover the medication. Do not use a dressing unless your healthcare provider specifically recommends that you do so.

Clobex Drug Information

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