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Clobetasol Propionate Foam Side Effects

Many people tolerate clobetasol propionate foam well. However, side effects may occur and can include burning or other skin reactions. This medicine can also suppress the adrenal glands, which may cause weight gain, fluid retention, or muscle loss. There are also some other potentially serious problems that should be reported to a healthcare provider immediately, including infections, ruptured tendons, and difficulty breathing.

An Introduction to Side Effects of Clobetasol Propionate Foam

Just like any medicine, clobetasol propionate foam (Olux®) can cause side effects. However, not everyone who uses the medication will have problems. In fact, most people tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider.
(This article covers many, but not all, of the possible side effects with clobetasol propionate foam. Your healthcare provider can discuss a more complete list with you.)

Clobetasol Propionate Foam and HPA Suppression

Using steroids like clobetasol propionate foam over long periods of time can cause a different set of side effects, sometimes known as hypothalamic-pituitary adrenal suppression (HPA suppression), or Cushing's syndrome. These side effects are most likely to be seen in people who use clobetasol propionate foam over a large area of the body for a long period of time (more than two weeks). Some of the problems seen with long-term use might include:
  • Suppression of the immune system (perhaps leading to infections or other problems)
  • Weight gain
  • Bulging eyes
  • Fluid retention
  • Osteoporosis
  • Loss of muscle
  • Fat deposits on the face and back (causing a round face and a fatty hump on the back of the neck)
  • Diabetes
  • Cataracts
  • Stunted growth (in children).
Clobetasol propionate foam is a highly potent steroid and is probably more likely to cause these side effects, compared to less potent steroids. This is why it is recommended only for short-term use (two weeks or less).

Clobetasol Propionate Foam Information

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