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Cinryze and Breastfeeding

Little information is available on the safety of using Cinryze while breastfeeding. However, it is thought that if the drug does pass through breast milk, it would do so in small amounts. It is also believed that the medicine would be destroyed in the infant's stomach. If you do use Cinryze while nursing, watch for any possible side effects in your child.


Can Breastfeeding Women Use Cinryze?

Cinryze® (C1 esterase inhibitor) is a prescription injectable medication used to help prevent the sudden attacks of pain and swelling that can occur in people with a condition known as hereditary angioedema (HAE). At this time, it is unknown whether Cinryze passes through breast milk.

More Information About Cinryze and Breastfeeding

Very little information is available about Cinryze and breastfeeding. The medication has not been studied in breastfeeding women. Therefore, it is unknown whether it passes through breast milk or if it would potentially harm a nursing child.
There have been reports of women using C1 esterase inhibitors such as Cinryze as needed to treat attacks associated with hereditary angioedema during breastfeeding. In these reports, no problems occurred in the nursing infants.
Based on the properties of Cinryze, if the drug does pass through breast milk, it would only be expected to do so in small amounts. In addition, any drug found in breast milk would likely be destroyed in the infant's stomach or intestines and not absorbed into the infant's bloodstream.
In general, Cinryze is probably safe for use during breastfeeding. In fact, some experts consider C1 esterase inhibitors the medications of choice for both treating and preventing HAE attacks in women who are nursing.
If your healthcare provider says it is okay to breastfeed during Cinryze treatment, make sure to watch for any possible side effects in your nursing child. Let your child's healthcare provider know if side effects occur, such as:
  • Rash
  • Nausea and vomiting
  • Fever
  • Difficulty feeding
  • Unexplained or excessive crying.
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Cinryze Medication Information

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