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Side Effects of Alefacept

Although most people don't have any problems while taking alefacept, side effects are possible. In clinical studies that compared alefacept to an injection with no active ingredient, common side effects included sore throat, nausea, and cough, among others. Serious reactions are also possible -- notify your healthcare provider right away if you experience chest pain, yellow skin, or difficulty breathing.

An Introduction to Side Effects of Alefacept

As with any medicine, side effects are possible with alefacept (Amevive®). However, not everyone who takes the medication will have problems. In fact, most people tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider.
(This article covers many, but not all, of the possible alefacept side effects. Your healthcare provider can discuss a more complete list with you.)

Alefacept Side Effects to Report

Some side effects with alefacept, although occurring infrequently, are potentially serious and should be reported immediately to your healthcare provider. These include but are not limited to:
  • Low T-cell blood counts, which may increase the risk of infection. Your healthcare provider should check your T-cell count before you begin treatment and every two weeks while you are taking alefacept).
  • Symptoms of an infection, such as a cough, chills, fever, or weakness.
  • Cancer symptoms of any type.
  • Symptoms of liver problems, such as:
    • Yellow eyes
    • Yellow skin (jaundice)
    • Upper-right abdominal pain (stomach pain)
    • Elevated liver enzymes (found using a blood test).
  • Signs of an allergic reaction, including:
    • An unexplained rash
    • Hives
    • Itching
    • Wheezing or difficulty breathing
    • Unexplained swelling.

Alefacept Drug Information

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