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Xolegel Warnings and Precautions

If your healthcare provider recommends seborrhea treatment with Xolegel, make sure he or she knows if you have any allergies or if you are pregnant or breastfeeding. Other precautions associated with using Xolegel safely include warnings of potential skin reactions or a worsening of seborrhea. Discuss your complete medical history with your healthcare provider before starting treatment with this medicine.

What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to using Xolegel® (ketoconazole gel) if you:
 
  • Are pregnant or thinking of becoming pregnant
  • Are breastfeeding
  • Have any allergies, including to foods, dyes, or preservatives.
 
You should also tell your healthcare provider about all other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.
 

Specific Precautions and Warnings for Xolegel

Some warnings and precautions to be aware of prior to using this product include the following:
 
  • Large oral doses of ketoconazole (the active ingredient in Xolegel) can cause liver problems and hormonal imbalances, although these problems have not been seen with ketoconazole products applied to the skin like Xolegel.
 
  • Xolegel can cause allergic reactions or other skin reactions. Let your healthcare provider know if you have new or different skin problems while using this medication. Also, let him or her know if your seborrhea does not improve or seems to be getting worse.
 
  • The gel is flammable. Avoid flames or smoking while applying the medication and immediately afterwards. Do not puncture the can or expose it to high temperatures.
 
 
  • Xolegel is a pregnancy Category C medication. This means that it may not be safe for use during pregnancy, although the full risks are currently unknown (see Xolegel and Pregnancy).
 
  • It is unknown if Xolegel is safe for use while breastfeeding. Therefore, if you are breastfeeding or plan to start, discuss this with your healthcare provider prior to using this product (see Xolegel and Breastfeeding).
 

Xolegel Medication Information

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