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Vorinostat Dosage

Chemotherapy treatment with vorinostat usually begins with a dosage of 400 mg taken once daily. However, if you start to experience bothersome or serious side effects, your healthcare provider may reduce your amount to 300 mg once daily or less. This prescription drug comes as a capsule and should be taken with food.

An Introduction to Your Dosage of Vorinostat

The dose of vorinostat (Zolinza®) your healthcare provider recommends will be based largely on how well you tolerate the medicine. As is always the case, do not adjust your dosage unless your healthcare provider specifically tells you to do so.

Vorinostat Dosing Guidelines

The usual recommended dosage of vorinostat for treating cutaneous T-cell lymphoma is 400 mg once daily. Your healthcare provider may reduce this amount to 300 mg once daily, or even 300 mg five days a week, if you experience bothersome vorinostat side effects. Treatment usually continues as long as the medicine is working and is not causing serious side effects.

General Information on Taking Vorinostat

Some considerations to keep in mind during treatment with vorinostat include the following:
  • This medication comes in the form of a capsule. It is usually taken by mouth once a day.
  • You should take vorinostat with food.
  • Try to take your dose at about the same time each day to keep an even level of the drug in your bloodstream.
  • Vorinostat should be swallowed whole; do not open, crush, or chew the capsules.
  • Try to drink eight 8-ounce glasses of fluid each day during treatment to help prevent dehydration.
  • For the medication to work properly, it must be taken as prescribed. Do not stop taking it without first talking to your healthcare provider.
  • If you are unsure about anything related to your dosage or vorinostat dosing in general, please talk to your healthcare provider or pharmacist.
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Vorinostat Drug Information

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