Cancer and Vorinostat
Some adults may receive a medicine called vorinostat (Zolinza®) to treat a cancer of the blood that affects the skin. Specifically, this prescription drug is approved to treat a type of non-Hodgkin's lymphoma called cutaneous T-cell lymphoma.
Although this chemotherapy drug has not been shown to improve survival and is not a cure for this form of cancer, vorinostat may help improve skin problems caused by this lymphoma. People with cutaneous T-cell lymphoma usually have red, itchy, rash-like patches of skin. They may also have tumors on the skin. In some cases, the lymph nodes may be swollen.
Vorinostat works by altering the structure of important proteins involved in gene expression -- the process by which the information contained in genes is interpreted. It may stop cancer cells from reproducing and cause cell death.