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Pediatric and Off-Label Indications for Ustekinumab

How Does Ustekinumab Work?

Ustekinumab belongs to a group of drugs known as monoclonal antibodies. These antibodies bind to IL-12 and IL-23, two naturally occurring inflammatory proteins (technically known as cytokines). By binding to IL-12 and IL-23, ustekinumab prevents these two cytokines from binding to other cells in the body. This action slows down the production of skin cells and decreases inflammation.

Ustekinumab Use in Children

This medication is approved only for people age 18 and older. Talk with your child's healthcare provider about the benefits and risks of using ustekinumab in children.

Is Ustekinumab Used for Off-Label Reasons?

On occasion, your healthcare provider may recommend this product for something other than plaque psoriasis. Theoretically, ustekinumab might be beneficial (and may be tried in an off-label fashion) for treating other types of psoriasis.

Ustekinumab Drug Information

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