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Understanding How Ustekinumab Works and Safety Concerns

What Should I Tell My Healthcare Provider Before Taking It?

You should talk with your healthcare provider prior to taking this drug if you have:
 
  • A history of tuberculosis
  • Any current infection
  • Infections that come and go, such as cold sores
  • Any disease that affects the immune system, such as diabetes, cancer, HIV, or AIDS
  • A history of any type of cancer
  • Plans to receive vaccinations
  • Any allergies, including to food, dyes, or preservatives.
     
Also, let your healthcare provider know if you are:
 
Make sure to tell your healthcare provider about all of the medicines you take, including prescription and nonprescription medications, vitamins, and herbal supplements.
 
(Click Precautions and Warnings With Ustekinumab to learn more, including information on who should not take the drug.)
 

How Does Ustekinumab Work?

Ustekinumab belongs to a group of drugs known as monoclonal antibodies. These antibodies bind to IL-12 and IL-23, two naturally occurring inflammatory proteins (technically known as cytokines). By binding to IL-12 and IL-23, the medicine prevents these two cytokines from binding to other cells in the body. This action slows down the production of skin cells and decreases inflammation.
 

Ustekinumab Drug Information

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