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Reported Reactions to Topical Fluticasone Propionate

Common Side Effects

Topical fluticasone propionate has been studied extensively in clinical trials. In these studies, one group of people received the drug, while another group was given a placebo (an ointment, cream, or lotion that did not contain any active ingredients). As a result, it was possible to see what side effects occurred, how often they appeared, and how they compared to the placebo.
In clinical trials, the most common side effects of fluticasone propionate cream included:
  • Facial spider veins -- in up to 4.9 percent of people
  • Skin irritation -- up to 2.9 percent
  • Burning -- up to 2 percent
  • Redness -- up to 2 percent
  • Nonfacial spider veins -- up to 2 percent
  • Hives -- up to 2 percent.
In clinical trials, there were no "common" side effects of fluticasone propionate ointment, which means none of the side effects occurred in more than 1 percent of people. However, some problems were reported and included:
  • Itching
  • Burning
  • Increased sweating
  • Redness
  • Hives
  • Irritation
  • Lightheadedness.
In clinical trials, the most common fluticasone propionate lotion side effects included:
  • Dry skin on multiple areas of the body -- in up to 7 percent of people
  • Stinging at the application site -- up to 5 percent
  • Common cold -- up to 4 percent
  • Influenza (the flu) -- up to 2 percent
  • Damaged skin (caused by scratching or rubbing) -- up to 2 percent.
For all forms of topical fluticasone propionate, side effects are more likely to occur if a dressing, such as a bandage, is used to cover the medication. Do not use a dressing or a bandage unless your healthcare provider specifically recommends it.

Topical Fluticasone Propionate Information

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