Drug Interactions With Terbinafine

When various medicines are taken together, it is possible to develop negative drug interactions. With terbinafine, interactions may occur if it is combined with chloroquine, captopril, beta blockers, or dextromethorphan. These interactions can increase the level of medicines in your blood, which can lead to increased risks for side effects. If drug interactions with terbinafine are a concern, your healthcare provider may adjust your dosages.

 

Terbinafine Drug Interactions: An Overview

Terbinafine hydrochloride (Lamisil®) can potentially interact with many drugs. Some of the drugs that may lead to terbinafine interactions include:
 
  • Beta blockers, such as:
o Bisoprolol (Zebeta®)
o Nadolol (Corgard®)
o Sotalol (Betapace®)
o Timolol (Blocadren)
  • Certain medications for arrhythmias (irregular heart rhythms), including:
o Felcainide (Tambocor®)
o Lidocaine (Xylocaine®)
o Procainamide (Procanbid®)
o Propafenone (Rythmol®)
o Mexiletine (Mexitil®)
  • Certain medications for attention deficit hyperactivity disorder (ADHD), such as:
o Atomoxetine (Straterra®)
o Methylphenidate (Concerta®, Daytrana®, Metadate®, Methylin®, Ritalin®)
o Fluoxitine (Prozac®)
  • Warfarin (Coumadin®, Jantoven®).
     
(Drug Interactions With Terbinafine Continued: Page 2)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;