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Spinosad Warnings and Precautions

It is important to know that eye irritation, skin rashes, and allergic reactions are possible when using spinosad to treat lice. In addition, women who are pregnant or breastfeeding should consult their healthcare provider before using this product. Understanding precautions and warnings with spinosad helps ensure a safe, effective treatment process.

What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to using spinosad (Natroba®) if you have any:
  • Skin conditions
  • Allergies, including to medications, foods, dyes, or preservatives.
Also, let your healthcare provider know if you are:
  • Pregnant or thinking of becoming pregnant
  • Breastfeeding.
You should also be sure to tell your healthcare provider about all of the medications you take, including prescription and nonprescription medicines, vitamins, and herbal supplements.

Specific Warnings and Precautions With Spinosad

Some precautions and warnings to be aware of with spinosad include the following:
  • This medication contains benzyl alcohol, an ingredient that can be dangerous to newborns, particularly premature newborns. Spinosad is not approved for children under the age of four. It should never be used for babies under the age of six months.
  • Spinosad may irritate the eyes. Be sure to keep the product away from the eyes. If eye exposure occurs, immediately flush the eyes with water and contact your healthcare provider if eye irritation persists.
  • Some people may be sensitive to this medication; it can cause rashes and allergic reactions.
  • Spinosad is unlikely to react with other medications (see Spinosad Drug Interactions).
  • This product is a pregnancy Category B medication, which means it is probably safe to use during pregnancy, although the full risks are currently unknown. If you are pregnant, check with your healthcare provider before using spinosad (see Natroba and Pregnancy for more information).
  • It is unknown if spinosad passes through breast milk. Therefore, if you are breastfeeding or plan to start, check with your healthcare provider (or your child's healthcare provider) before using this medication (see Natroba and Breastfeeding).
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