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What You Need to Know About Spinosad

Important Information for Your Healthcare Provider

You should talk with your healthcare provider prior to using spinosad if you have any:
  • Skin conditions
  • Allergies, including to medications, foods, dyes, or preservatives.
Also, let your healthcare provider know if you are:
Make sure to tell your healthcare provider about all of the medications you take, including prescription and nonprescription medicines, vitamins, and herbal supplements.
(Click Spinosad Warnings and Precautions to learn more, including information on who should not use the drug.)

How Does It Work?

Spinosad causes lice to become hyperactive, after which they become paralyzed and die. It is derived from the fermentation of a certain type of soil bacteria. Spinosad is also used as an insecticide in lawn and garden products.

How Effective Is Spinosad?

Two different clinical studies have compared spinosad to permethrin cream (Nix®) for treating head lice. In both studies, spinosad was much more effective. In one study, 84.6 percent of people given spinosad were free of lice 14 days after treatment, compared to only 44.9 percent of those given Nix. The other study showed similar results.
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