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Promethazine Tablets

Promethazine hydrochloride (Phenergan®) is prescribed to treat a wide range of conditions, including allergies, motion sickness, and nausea or vomiting. Promethazine comes in tablet, syrup, rectal suppository, and injectable form. Depending on the specific condition being treated, this medication is generally taken one to three times a day.
Promethazine is both an antihistamine and a phenothiazine. Many of the drug's effects are likely due to its antihistamine activity. Although phenothiazines are usually used as antipsychotic medications, promethazine has little dopamine-blocking activity. This medicine also blocks acetylcholine receptors, which is probably why it helps to alleviate nausea and motion sickness.
Just like any medicine, promethazine may cause side effects. However, not everyone who takes the drug will experience problems. If negative reactions do occur, in most cases, they are minor and either require no treatment or can be easily treated. Commonly reported side effects include, but are not limited to:
  • Drowsiness
  • Confusion
  • Dry mouth.
(Click Promethazine for more information on when and how to use promethazine tablets, syrup, and rectal suppositories; to learn about the warnings associated with this medicine; and to find out what you should be aware of before starting treatment.)
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