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Promethazine for Nausea

Promethazine hydrochloride (Phenergan®) is licensed for a wide variety of different conditions, including nausea and vomiting. Specifically, healthcare providers may prescribe promethazine for nausea and vomiting associated with surgery and certain types of anesthesia. Although the medicine is not approved to treat nausea or vomiting due to other causes, it is frequently prescribed for such uses.
If you have severe vomiting and nausea, promethazine rectal suppositories may be the best option. This form will eliminate the difficulty of taking the medication by mouth, which might worsen nausea and vomiting, and avoid the question of what to do if the drug is vomited up. In the hospital setting, an IV form may also be given for the treatment and/or prevention of nausea and vomiting.
(Click Phenergan for Nausea for information on how promethazine works for nausea and to find out if this medication is safe for treating nausea in children.)
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