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Drug Interactions With OnabotulinumtoxinA

Problems can occur when onabotulinumtoxinA is combined with other drugs, such as Nimbex, Myobloc, and certain antibiotics. These interactions can decrease the effectiveness of the medications and increase your risk for side effects. To reduce your risk of onabotulinumtoxinA drug interactions, make sure your healthcare provider is aware of all other medicines you are currently taking.

Interactions With OnabotulinumtoxinA: An Overview

OnabotulinumtoxinA (Botox®) can potentially interact with a few other medicines. Some of the medications that may lead to drug interactions with this product include:
  • Aminoglycoside antibiotics, such as:
    • Amikacin (Amikin®)
    • Gentamicin
    • Kanamycin (Kantrex®)
    • Neomycin (Neo-Fradin®)
    • Streptomycin
    • Tobramycin
  • RimabotulinumtoxinB, previously known as botulinum toxin type B (Myobloc®)
  • Neuromuscular-blocking medications, such as:
    • Atracurium
    • Cisatracurium (Nimbex®)
    • Doxacurium (Nuromax®)
    • Mivacurium (Mivacron®)
    • Pancuronium
    • Rocuronium (Zemuron®)
    • Succinylcholine (Anectine®, Quelicin®)
    • Tubocurarine
    • Vecuronium (Norcuron®).

More Information on OnabotulinumtoxinA Drug Interactions

The following sections explain in detail the potentially negative interactions that can occur when onabotulinumtoxinA is combined with any of the drugs listed above.
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OnabotulinumtoxinA Drug Information

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