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Treatment Instructions for Mupirocin

What Should I Tell My Healthcare Provider Before Using It?

Prior to using this medication, tell your healthcare provider if you have:
  • Kidney disease, such as kidney failure (renal failure)
  • A severe burn or large open wound
  • Any allergies, including to foods, dyes, or preservatives.
Also, let your healthcare provider know if you are:
Make sure to tell your healthcare provider about any other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.
(Click Mupirocin Warnings and Precautions to learn more, including information on who should not take the drug.)

How Does Mupirocin Work?

This medication works by interfering with bacterial protein synthesis. This means that it stops bacteria from making important proteins. More specifically, mupirocin works by binding to an important bacterial enzyme known as isoleucyl transfer-RNA synthetase. It works against a wide range of bacteria, including (most notably) MRSA.

When and How to Take Mupirocin

General considerations to keep in mind during treatment with mupirocin include the following:
  • This medication comes in skin cream, skin ointment, and nasal ointment forms.
  • The skin products are usually applied to the affected area three times daily. A dressing or bandage may be applied to cover the area, if desired.
  • The nasal ointment is applied into the nose twice daily for five days. After applying the ointment, repeatedly pinch and release the sides of the nose for one minute. This spreads the ointment throughout the nostrils.
  • For mupirocin to work properly, it must be taken as prescribed. Do not miss doses or stop taking this antibiotic earlier than your healthcare provider recommends, as bacterial resistance may develop.
A Dose of Reassurance for Parents of Picky Eaters

Mupirocin Drug Information

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