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Mupirocin and Pregnancy

The Food and Drug Administration considers mupirocin (Bactroban) a pregnancy Category B medication, based on the results of animal studies. Even when very high doses were given to pregnant animals, problems did not occur. However, because each woman's situation is unique, it is best to discuss the benefits and risks with a healthcare provider.

Is Mupirocin Safe During Pregnancy?

Mupirocin (Bactroban®) is a prescription antibiotic often used to treat skin infections. Studies in animals suggest that the drug is probably safe for use during pregnancy, although the full risks are not currently known.
 

What Is Pregnancy Category B?

The U.S. Food and Drug Administration (FDA) uses a category system to classify the possible risks to a fetus when a specific medicine is taken during pregnancy. Pregnancy Category B is given to medicines that have not been adequately studied in pregnant humans but do not appear to cause harm to the fetus in animal studies.
 
In addition, medications that have been shown to be safe for use in pregnancy in humans but have caused problems in laboratory animals are given a Category B rating.
 
In general, most pregnancy Category B drugs are considered safe for pregnant women. For instance, acetaminophen (Tylenol®), usually the preferred painkiller during pregnancy, is a pregnancy Category B medicine.
 
Studies in pregnant laboratory animals did not suggest that mupirocin increases the risk of birth defects, miscarriages, or other problems for the fetus, even when high doses were used.
 
However, it is important to note that animals do not always respond to medicines the same way that humans do. Therefore, a pregnancy Category B medicine should be given to a pregnant woman only if the healthcare provider believes that the benefits to the woman outweigh any possible risks to the unborn child.
 
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