Is Mangosteen Safe?

Many people may wonder how safe mangosteen is. Before using mangosteen medicinally, it is important to understand that this tropical fruit is considered a food or dietary supplement, which means that it is not as closely regulated as prescription or non-prescription drugs. Therefore, mangosteen can be sold without any proof that it is safe or effective. Also, just because mangosteen is a "natural" product, it does not mean that it is safe for everyone.

Is Mangosteen Safe?

Mangosteen is a tropical fruit prized for its intense taste. It is eaten as a fruit, consumed as a juice, or taken as a dietary supplement. Occasional consumption of mangosteen is probably safe for most people. However, you should talk with your healthcare provider prior to taking mangosteen (especially mangosteen supplements) if you:
 
  • Have any allergies, including allergies to foods, dyes, or preservatives
  • Have any chronic or severe medical condition
  • Are pregnant or thinking of becoming pregnant
  • Are breastfeeding.
     
You should also make sure to tell your healthcare provider about any other medicines you are taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.
 

Specific Safety Warnings and Precautions With Mangosteen

Some warnings and precautions to be aware of concerning the safety of mangosteen include the following:
 
  • There has been one report of severe lactic acidosis (a very dangerous condition) possibly related to mangosteen juice (see Mangosteen Side Effects for more information).
     
  • As dietary supplements or food products, mangosteen is not as closely regulated as prescription (or non-prescription) drugs. They can be marketed without any proof that they are either safe or effective. Do not assume that just because a product is sold or advertised in the United States that it is safe or effective. Make sure to look for mangosteen products from a reputable manufacturer. Your pharmacist is a good resource for information about which manufacturers are the most reputable.
     
  • If you have a chronic or severe medical condition, it is always a good idea to check with your healthcare provider before taking any medication or supplement, including mangosteen.
     
  • It is not known if mangosteen is safe for pregnant or breastfeeding women (see Mangosteen and Pregnancy and Mangosteen and Breastfeeding).
     
(Is Mangosteen Safe? Continued: Page 2)
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;
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