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Elidel Drug Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when Elidel is combined with any of the drugs listed above.
People who use Elidel may experience facial flushing (a sudden redness and warmth of the skin) after consuming alcohol. Talk to your healthcare provider if facial flushing becomes a problem for you. He or she may be able to recommend ways to reduce the flushing effects, such as taking low-dose aspirin.
CYP 3A4 Inhibitor Medications
The liver breaks down Elidel using enzymes known as CYP 3A4 enzymes. Medications known as CYP 3A4 inhibitors can decrease the activity of these enzymes. Thus, combining Elidel with one of these drugs may increase the level of Elidel in your body, potentially increasing your risk for side effects. The risk for this interaction is generally low, as only a small amount of Elidel is expected to be absorbed into the bloodstream after normal use. However, some people may absorb more than expected.
Immunosuppressant Medications
It is generally recommended that people taking other immunosuppressant medications not use Elidel, due to the increased risk for infections, lymphoma (cancer of the lymph nodes), and skin cancer. The risk for these side effects is greater with higher immunosuppressant doses and long-term immunosuppressant use. Talk to your healthcare provider before using Elidel with another immunosuppressant medicine.

Final Thoughts

It is possible that not all drug interactions with Elidel were discussed in this article. Therefore, you should talk with your pharmacist or healthcare provider about any specific interactions that may apply to you.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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