Skin Home > Cancer and Dacarbazine

Adults who have been diagnosed with certain types of cancer may receive dacarbazine (DTIC-Dome®) as part of their chemotherapy treatment. It is specifically approved to treat malignant melanoma (a type of skin cancer) that has spread to other areas (metastasized). The medication is also approved for use in combination with other medications to treat Hodgkin's disease. Dacarbazine is thought to work by interfering with DNA replication, which is a process necessary for cells to copy themselves and divide.
 
There are also some off-label (unapproved) uses for dacarbazine, such as treating thyroid cancer, pancreatic cancer, and other types of cancer.
 
(Click What Is Dacarbazine Used For? for a closer look at how dacarbazine is used for cancer treatment. This article also lists other possible uses and talks about whether the medicine is safe for use in children.)
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Last reviewed by: Kristi Monson, PharmD;
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