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Kalbitor Uses

Adults age 16 and older may use Kalbitor to treat swelling that occurs due to sudden hereditary angioedema (HAE) attacks. Kalbitor works by blocking a certain chemical that causes the veins to leak liquid during an HAE attack. This drug can help relieve pain and swelling of the hands, face, feet, and abdomen (stomach).

What Is Kalbitor Used For?

Kalbitor® (ecallantide) is an injectable medication approved to treat sudden hereditary angioedema (HAE) attacks in individuals age 12 and older.
 
Hereditary angioedema (HAE) is a rare genetic disease in which various parts of the body, such as the hands, face, feet, and airway, suddenly swell. During HAE attacks, people can also have swelling in their small intestines, which can cause abdominal (stomach) pain, nausea, and vomiting.
 
People with HAE have a defect in a gene that controls the production of a protein in the body called C1 inhibitor. In someone with HAE, too little C1 inhibitor is made or it doesn't work correctly, which causes small blood vessels in the body to leak fluids into the surrounding tissue. 
 
Currently, there are three different types of medication that are typically used to treat HAE. They are given either by an injection just below the skin (subcutaneously) or into a vein (intravenously, or by IV). The first type is called a C1 esterase inhibitor replacement protein. As its name suggests, it replaces a protein that is missing or is not working properly in someone with HAE. This type of medication is given in a vein at the time of an attack, or to prevent an attack from occurring.
 
The second type of drug is called a bradykinin inhibitor. Firazyr® (icatibant) is currently the only available bradykinin inhibitor. It is given as an injection into a vein. This medication blocks the activity of a chemical in the body known as bradykinin. Too much bradykinin causes swelling in the body.
 
The third type of medication is a kallikrein inhibitor. Kalbitor is this type of medication.
 

Kalbitor Medication Information

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