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Istodax Drug Interactions

Your healthcare provider needs to know about all other medications, vitamins, and supplements you are taking before you can start treatment with Istodax. Drug interactions can occur if Istodax is combined with various products, including certain medications that affect liver enzymes, St. John's wort, and warfarin. Some of these reactions may decrease the effectiveness of Istodax or increase your risk for serious side effects.

An Overview of Interactions With Istodax

Istodax® (romidepsin) may react with a number of other products. Some of the drugs that can interact with Istodax include but are not limited to:
 
  • CYP 3A4 inducer medications, such as:
 
 
  • CYP 3A4 inhibitor medications, such as:
 
 
  • Medications that cause a certain change in the heart rhythm known as QT prolongation (see QT-Prolonging Medications for a list of such drugs)
  • P-glycoprotein inducers, such as:
 
 
  • P-glycoprotein inhibitors, such as:
 
 
 
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Istodax Medication Information

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