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Istodax and Breastfeeding

Although it is unknown whether Istodax (romidepsin) passes through human breast milk, it is thought that it would to some extent. Although the amount that passes through breast milk is probably quite low, this medication has the potential to cause dangerous side effects. Due to the unknown risks, the manufacturer advises that women not breastfeed during Istodax treatment.

Can Breastfeeding Women Receive Istodax?

Istodax® (romidepsin) is a prescription medication used in the treatment of cutaneous T-cell lymphoma and peripheral T-cell lymphoma. It belongs to a group of drugs known as histone deacetylase inhibitors.
It is unknown if Istodax passes through breast milk. The manufacturer recommends women not breastfeed during treatment.

More Information About Istodax and Breastfeeding

Istodax has not been studied in breastfeeding women. Therefore, it is unknown if the medicine passes through breast milk or would harm a nursing child. Based on the properties of the drug, it can be expected to pass through breast milk to some extent, although the amount may be quite low.
Until more information is known about Istodax and breastfeeding, it may be safest to avoid nursing while using this medicine. However, because Istodax is usually only given approximately once a week, a woman may choose to breastfeed on days she does not receive a dose.
Talk to your healthcare provider about this strategy if you are interested in breastfeeding on a nontreatment day. Your healthcare provider can discuss the pros and cons of breastfeeding between doses and recommend how long you should wait from the end of the dose until you breastfeed. Keep in mind that you may need to "pump and dump" during treatment days in order to maintain milk production.
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Istodax Medication Information

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