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Pediatric and Off-Label Indications for Hydrocortisone Butyrate

Can Children Use Hydrocortisone Butyrate?

Hydrocortisone butyrate lotion and Lipocream are approved for use in children as young as three months old to treat atopic dermatitis only. Hydrocortisone butyrate ointment, lotion, and cream are not specifically approved for use in children.
Hydrocortisone butyrate is not approved to treat a diaper rash and should never be applied to the diaper area, as doing so can increase the risk for side effects. Children are at an increased risk for serious side effects of steroids.

Are There Off-Label Reasons to Use Hydrocortisone Butyrate?

On occasion, your healthcare provider may recommend this medicine for something other than the approved uses. This is known as an "off-label" use. For instance, hydrocortisone butyrate is sometimes prescribed off-label to treat the following conditions:
  • Penile adhesions or phimosis (typically in young boys)
  • Labial adhesions (typically in young girls)
  • Vitiligo.
In addition, using hydrocortisone butyrate lotion for psoriasis, eczema, or anything except atopic dermatitis would be an off-label use, as it is approved only for atopic dermatitis treatment.

Hydrocortisone Butyrate Drug Information

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