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Precautions and Warnings With Fluticasone Propionate Cream

Fluticasone propionate cream is not suitable for everyone, so make sure your healthcare provider knows about any allergies you have, any medications you are taking, or if you are pregnant or breastfeeding. Other precautions and warnings with fluticasone propionate cream involve complications this steroid might cause with long-term use. This medicated skin cream can also cause the body to stop making its own natural steroids.

What Should I Tell My Healthcare Provider Before Using Fluticasone Propionate Cream?

You should talk with your healthcare provider prior to using fluticasone propionate cream (Cutivate Cream®) if you:
 
  • Are breastfeeding
  • Are pregnant or thinking of becoming pregnant
  • Have any allergies, including to foods, dyes, or preservatives.
 
You should also tell your healthcare provider about all other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.
 

Specific Fluticasone Propionate Cream Precautions and Warnings

Some warnings and precautions to be aware of before using this medicine include the following:
 
  • Fluticasone propionate cream contains an inactive ingredient (imidurea) that breaks down into formaldehyde. This should not be a significant concern, except for people who are allergic to formaldehyde.
 
  • This product is a steroid and can cause serious side effects, such as Cushing's syndrome or diabetes. Although this is more likely to occur with oral or injectable steroids, it is still possible with topical steroids, including fluticasone propionate cream. The more you apply and the longer you use the drug, the more likely these problems are to occur. Covering the medicine with a dressing, which is not recommended, may also increase this risk.
 
  • If you use this medication for an extended period, it may lead to Cushing's syndrome (a group of symptoms caused by prolonged exposure to steroids). Contact your healthcare provider if you develop signs of this condition, such as:
 
    • A rounded face
    • Unusual body fat distribution (more fat in the trunk, face, and neck, and less fat in the arms and legs)
    • High blood sugar levels.
 
  • Fluticasone propionate cream can suppress the body's ability to make natural steroids. This typically happens when large doses are used over a long period. In such circumstances, fluticasone propionate cream should be stopped gradually to give your body a chance to begin making its own natural steroids again. If this is not feasible, you might need to take an oral steroid for a while, after which you will slowly be weaned off the oral steroid.
 
  • Like all steroids, fluticasone propionate cream may slow down the growth rate of children and teenagers. Contact your child's healthcare provider if you are concerned about this. In general, children may be more susceptible to the side effects of steroids. Close monitoring is necessary for any child receiving such drugs long-term.
 
  • If you develop a skin infection while using fluticasone propionate cream, you will need to be treated with appropriate antibiotics or antifungal medications. If the infection does not clear up, you may need to stop using this product.
 
 
  • This product is a pregnancy Category C medication. This means that it may not be safe for use during pregnancy, although the full risks are currently unknown (see Cutivate Cream and Pregnancy).
 
  • It is unknown if this medicine passes through breast milk. Therefore, if you are breastfeeding or plan to start, discuss this with your healthcare provider prior to using the cream (see Cutivate Cream and Breastfeeding).
 

Fluticasone Propionate Cream Information

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