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Common and Long-Term Reactions to Fluticasone Propionate Cream

Common Side Effects

Fluticasone propionate cream has been studied extensively in clinical trials. In these studies, one group of people received the drug, while another group was given a placebo (a cream that did not contain any active ingredients). As a result, it was possible to see what side effects occurred, how often they appeared, and how they compared to the placebo.
In clinical trials, the most common fluticasone propionate cream side effects included:
  • Facial spider veins -- in up to 4.9 percent of people
  • Skin irritation -- up to 2.9 percent
  • Burning -- up to 2 percent
  • Redness -- up to 2 percent
  • Non-facial spider veins -- up to 2 percent
  • Hives -- up to 2 percent.
Other common side effects, occurring in 1 to 2 percent of people, included:
  • Infected eczema
  • Worsening of eczema
  • Stinging
  • Dry skin
  • Itching.
In general, adverse reactions are more likely to occur if a dressing, such as a bandage, is used to cover the medication. Do not use a dressing or a bandage unless your healthcare provider specifically recommends it.

Long-Term Side Effects of Fluticasone Propionate Cream

Using steroids like fluticasone propionate cream over long periods can cause a different set of side effects. These reactions are most likely to be seen in people who use this medicine over a large area of the body for a long time. Some of the problems seen with long-term use might include:
  • Weight gain
  • Bulging eyes
  • Fluid retention
  • Osteoporosis
  • Loss of muscle
  • Fat deposits on the face and back (causing a round face and a fatty hump on back of the neck)
  • Diabetes
  • Cataracts
  • Stunted growth (in children).
Keep in mind that these side effects are more common with systemic steroids, which are taken by mouth or injection, and are probably rare with fluticasone propionate cream when used as directed and for a short time.

Fluticasone Propionate Cream Information

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