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Drug Interactions With Fluticasone Propionate Cream
Taking certain drugs in combination with fluticasone propionate cream may result in negative interactions. For instance, fluticasone propionate cream can interfere with the effectiveness of medications such as corticorelin and aldesleukin. To help minimize any complications, tell your healthcare provider about any other medications, vitamins, or herbal supplements you are using before beginning treatment with this medicated skin cream.
Fluticasone propionate cream (Cutivate Cream®) is generally unlikely to react with other medications. However, there are a few potential drug interactions that may occur. Some of the products that can interfere with fluticasone propionate cream include but are not limited to:
- Aldesleukin (Proleukin®)
- Corticorelin (Acthrel®).
The following sections explain in detail the potentially negative interactions that can occur when fluticasone propionate cream is combined with any of the drugs listed above.
Aldesleukin
Corticosteroids, including fluticasone propionate cream, can make aldesleukin (a chemotherapy medication) less effective. In general, these medications should not be used together.
Corticorelin
Corticosteroids, including fluticasone propionate cream, can make corticorelin less effective. Corticorelin is used as a diagnostic agent in tests for Cushing's syndrome or other similar problems. If you are being tested for Cushing's disease, make sure your healthcare provider knows you have been using fluticasone propionate cream.
It is possible that not all fluticasone propionate cream drug interactions were discussed in this article. Therefore, you should talk with your pharmacist or healthcare provider about the specific interactions that may apply to you.
Written by/reviewed by: Kristi Monson, PharmD
Last reviewed by: Kristi Monson, PharmD



