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Precautions and Warnings With Fluocinolone Oil

Although fluocinolone oil can be an effective treatment, this medicine is not suitable for everyone. For instance, people who have diabetes or skin infections may not be able to use this medication safely. Other important warnings and precautions with fluocinolone oil involve potential drug interactions, risks for people with certain allergies, and possible dangers for pregnant or nursing women.

What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to using fluocinolone oil (Derma-Smoothe/FS®) if you have:
 
  • Any type of skin infection
  • Diabetes
  • Any allergies, including a peanut allergy or allergies to other foods, dyes, or preservatives.
 
Also, let your healthcare provider know if you are:
 
  • Pregnant or thinking of becoming pregnant
  • Breastfeeding.
 
You should also tell your healthcare provider about all other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.
 

Specific Fluocinolone Oil Precautions and Warnings

Some warnings and precautions to be aware of prior to using this medicine include the following:
 
  • Fluocinolone oil is a topical (applied to the skin) steroid. However, it can be absorbed through the skin and cause steroid side effects in the body. This is more likely to happen if the medicine is used for long periods of time or over large areas of the skin. Covering the medicine with a bandage or dressing may also increase the risk for steroid side effects. Do not use this medicine longer than recommended or more often than prescribed.
 
  • This medicine can increase sugar levels in your urine or blood, or cause diabetes, especially if used for longer periods of time. Contact your healthcare provider if you develop signs of high blood sugar (hyperglycemia), such as:
 
    • Increased thirst
    • Frequent urination
    • Blurred vision.
 
  • Using this medicine for an extended period of time could lead to Cushing's syndrome. Let your healthcare provider know if you develop signs of Cushing's syndrome, such as:
 
    • Weight gain around the midsection, upper back, or between the shoulder blades
    • A rounded face
    • Skin that seems thin or bruises easily.
 
  • Like other steroids, fluocinolone oil may suppress your body's ability to make natural steroids, especially if used in large doses for an extended period of time. Your healthcare provider may recommend certain tests to make sure you are not developing this or other side effects. In the event you do develop problems, you may need to take oral steroids for a period of time.
 
  • Children are more likely to absorb topical medicines, including fluocinolone oil, through the skin, potentially causing side effects. One such side effect is a delay in growth. If your child needs this medicine long-term, you may need to monitor your child's growth. Let your child's healthcare provider know if your child seems to be growing slower than expected.
 
  • Let your healthcare provider know if your condition worsens or does not improve within two weeks. Also, tell your healthcare provider if you develop severe skin irritation, such as redness, burning, itching, or dryness, or if your skin seems to be thinning or appears infected.
 
  • Fluocinolone oil may cause skin reactions, such as burning, stinging, redness, soreness, or itching, on areas of the skin where you apply the medicine. Contact your healthcare provider if you experience severe skin reactions, or if they do not go away after about a week.
 
  • This medication contains peanut oil. Make sure your healthcare provider knows if you have a peanut allergy.
 
  • Fluocinolone oil should only be applied on the skin. Avoid getting it into your eyes, nose, mouth, or other body openings. If you do get the oil in any of these areas, wipe away the medicine, and then rinse the area well with cold water.
 
  • Do not apply this medicine to the face, underarm, or groin area, unless directed by your healthcare provider. Do not use it to treat a diaper rash or apply it to the diaper area of a child. Doing so could cause the medicine to be absorbed through the skin, increasing the risk for side effects.
 
 
  • Fluocinolone oil is a pregnancy Category C medication, which means it may not be safe for use during pregnancy. Talk to your healthcare provider about the risks and benefits of using this product during pregnancy (see Derma-Smoothe and Pregnancy).
 
  • It is unknown if fluocinolone oil passes through breast milk. Therefore, if you are breastfeeding or plan to start, discuss this with your healthcare provider prior to using the oil (see Derma-Smoothe and Breastfeeding).
 

Fluocinolone Oil Information

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