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Potential Reactions to Erythromycin/Benzoyl Peroxide

Common Side Effects

Erythromycin/benzoyl peroxide has been studied extensively in clinical trials. In these studies, the side effects that occurred in people using erythromycin/benzoyl peroxide were carefully documented.
In clinical trials, the most commonly reported erythromycin/benzoyl peroxide side effects were skin reactions, including:
  • Dry skin -- in up to 7.6 percent of people
  • Redness, tingling, burning, or stinging -- up to 2.5 percent
  • Itching -- up to 2.5 percent
  • Eyelid inflammation, irritation, and itchiness -- up to 1.7 percent.
Other side effects reported in clinical trials included:
  • A sunburn or stinging when exposed to the sun
  • Skin peeling
  • Oily skin
  • Skin tenderness
  • Skin discoloration.

Final Thoughts

You may experience some or none of the side effects listed in this article. Unfortunately, there is no way for your healthcare provider to know beforehand if you will have problems with a medicine that you have never tried.
Therefore, make sure to let your healthcare provider know if you develop any side effects while using erythromycin/benzoyl peroxide or if something "just does not seem right." While it may not be related to the medication, your healthcare provider will be able to diagnose and treat the problem.

Erythromycin/Benzoyl Peroxide Information

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