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Safety Precautions With Erythromycin/Benzoyl Peroxide

What If I Overdose on This Medication?

An overdose of this medication may cause extreme skin irritation, but is unlikely to be extremely dangerous. However, it is important to seek medical attention if you believe you have overdosed on erythromycin/benzoyl peroxide or if you have taken this medication by mouth.
(Click Benzamycin Overdose for more information.)

What Should I Do If I Forget a Dose?

If you forget to use erythromycin/benzoyl peroxide one morning or evening, just skip that dose and continue with your regular schedule. Do not apply extra medication to make up for a missed dose; applying more medication does not increase the effectiveness of the drug and may irritate your skin.

How Does It Work?

Erythromycin/benzoyl peroxide contains a combination of two acne medications: erythromycin and benzoyl peroxide.
Erythromycin belongs to a group of medications known as macrolides. It works by binding to bacterial ribosomes, which are the parts of cells that make proteins. By binding to the ribosomes, erythromycin prevents proteins, which are needed for the bacteria to grow and multiply, from being made. This helps prevent acne-causing bacteria from growing on the skin.
Benzoyl peroxide is thought to work by killing Propionibacterium acnes (P. acnes), the bacterium that contributes to acne. P. acnes is an anaerobic bacteria, which means it lives without oxygen. Benzoyl peroxide is thought to release oxygen into the skin pores, which kills the bacteria. It also helps soften and peel away the outer layer of the skin, which can open up clogged pores and improve the skin's appearance.

Erythromycin/Benzoyl Peroxide Information

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