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Diflorasone Diacetate and Pregnancy

When steroids like diflorasone diacetate were given to pregnant animals, it increased the risk for birth defects, poor fetal growth, and other problems. However, using this medicine for just a few days on a small area of the body is not expected to cause problems. If you are pregnant and using diflorasone diacetate, it is best to use the smallest amount for the shortest time possible.

Can Pregnant Women Use Diflorasone Diacetate?

Diflorasone diacetate is a prescription skin medication approved for treating a number of different skin conditions, such as eczema and psoriasis. It is a steroid. At this time, it is unclear if the drug is safe for use during pregnancy. Steroids should be used only if necessary, at the lowest effective dose, and for the shortest time possible during pregnancy.
 

What Is Pregnancy Category C?

The U.S. Food and Drug Administration (FDA) uses a category system to classify the possible risks to a fetus when a specific medicine is taken during pregnancy. Pregnancy Category C is given to medicines that have not been studied in pregnant humans but do appear to cause harm to the fetus in animal studies.
 
In addition, medicines that have not been studied in any pregnant women or animals are automatically given a pregnancy Category C rating.
 
As mentioned, diflorasone diacetate is a steroid. Animal studies have shown that steroids may increase the risk of birth defects, such as cleft palate, and may cause other problems, such as poor fetal growth or decreased survival. Similar problems might also occur in humans, although the risk is probably smaller with topical steroids that are applied to the skin, like diflorasone diacetate.
 
While short-term use (a few days) of diflorasone diacetate applied to a small area of the body is probably not likely to cause problems (although this is not known for sure), extended use or use over a large area of the body should generally be avoided during pregnancy if possible.
 
Pregnancy and Pain

Diflorasone Diacetate Drug Information

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