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Precautions and Warnings With Desoximetasone Spray

Before beginning treatment with desoximetasone spray, you should understand that this drug may cause problems, such as serious side effects or allergic reactions. Other warnings to be aware of before using desoximetasone spray include safety precautions for women who are pregnant or nursing. Also, using this medicine for long periods of time may lead to a medical condition called Cushing's syndrome.

What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to using desoximetasone spray (Topicort®) if you:
 
  • Are breastfeeding
  • Are pregnant or thinking of becoming pregnant
  • Have any allergies, including to foods, dyes, or preservatives.
 
You should also tell your healthcare provider about all other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.
 

Specific Desoximetasone Spray Precautions and Warnings

Some warnings and precautions to be aware of before using this medicine include the following:
 
  • Desoximetasone spray is a steroid and can cause serious side effects. Although this is more likely to occur with oral or injectable steroids, it is still possible with topical steroids, including desoximetasone spray. The more you apply and the longer you use the drug, the more likely these problems are to occur. Covering the medicine with a dressing, which is sometimes recommended, may also increase this risk.
 
  • If you use this medication for an extended period of time, it may lead to Cushing's syndrome (a group of symptoms caused by prolonged exposure to steroids). Contact your healthcare provider if you develop signs of this condition, such as:
    • A rounded face
    • Unusual body fat distribution (more fat in the trunk, face, and neck, and less fat in the arms and legs)
    • High blood sugar levels.
 
  • Desoximetasone spray can suppress the body's ability to make natural steroids. This typically happens when large doses are used over a long period of time. In such circumstances, this spray should be stopped gradually to give your body a chance to begin making its own natural steroids again. If this is not feasible, you might need to take an oral steroid for a while, after which you will slowly be weaned off the oral steroid.
 
  • Like all steroids, desoximetasone spray may slow down the growth rate of children and teenagers. In general, children may be more susceptible to the side effects of steroids. Close monitoring is necessary for any child receiving long-term steroids. Desoximetasone spray is not approved for use in children. Less potent steroids are more appropriate.
   
  • Desoximetasone spray is a pregnancy Category C medication. This means that it may not be safe for use during pregnancy, although the full risks are currently unknown (see Topicort and Pregnancy).
 
  • It is unknown if desoximetasone spray passes through breast milk. Therefore, if you are breastfeeding or plan to start, discuss this with your healthcare provider prior to using the drug (see Topicort and Breastfeeding).
 

Desoximetasone Spray Information

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