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Dermatop and Pregnancy

A pregnant woman may use Dermatop (prednicarbate) if her healthcare provider believes that the benefits to the woman outweigh the risk to the fetus. If the drug is recommended, it should be used on the smallest area of skin possible for the shortest time. Steroids can cause problems during pregnancy; however, Dermatop is applied to the skin, so the risk is expected to be low.

Can Pregnant Women Use Dermatop?

Dermatop® (prednicarbate) is a prescription topical steroid approved for treating itching and inflammation due to a wide variety of skin conditions. Based on information currently available, it is unclear if the drug is safe for use during pregnancy. As with most medications, Dermatop should be used only if necessary, at the lowest effective dose, and for the shortest possible time during pregnancy.

What Is Pregnancy Category C?

The U.S. Food and Drug Administration (FDA) uses a category system to classify the possible risks to a fetus when a specific medicine is taken during pregnancy. Pregnancy Category C is given to medicines that have not been studied in pregnant humans but do appear to cause harm to the fetus in animal studies.
In addition, medicines that have not been studied in any pregnant women or animals are automatically given a pregnancy Category C rating.
Animal studies have shown that steroids, including Dermatop, may increase the risk of birth defects, such as cleft palate, and may cause other problems, such as poor fetal growth or decreased survival. Similar problems might also occur in humans, although the risk is probably smaller with topical steroids that are applied to the skin, like Dermatop. In studies that specifically used Dermatop, very high doses caused birth defects and fetal death in animals.
While short-term use (a few days) of this drug, applied to a small area of the body, is probably unlikely to cause problems (although this is not known for sure), extended use or use over a large area of the body should probably be avoided during pregnancy, if possible.
Pregnancy and Pain

Dermatop Medication Information

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