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Specific Drugs That Interfere With Denileukin Diftitox

More Detail on Drug Interactions With Denileukin Diftitox

The following sections explain in detail the potentially negative interactions that can occur when denileukin diftitox is combined with any of the drugs listed above.
Amphotericin B
Combining denileukin diftitox with amphotericin B could increase your risk for amphotericin B side effects, such as kidney damage, low blood pressure (hypotension), and breathing problems. Your healthcare provider may choose to monitor you more closely if you use these medicines together.
Biologic and Immunologic Medications
Combining denileukin diftitox with biologic and immunologic medications could increase your risk for potentially serious side effects, including low blood cell counts and infections. Your healthcare provider may choose to monitor you more closely if you use these medications together.
Because echinacea is thought to work by stimulating the activity of the immune system, it may decrease the effectiveness of denileukin diftitox. Do not take echinacea during chemotherapy treatment without first talking to your healthcare provider.
Live Vaccinations
Live vaccines contain live viruses or bacteria. If you receive a live vaccine during denileukin diftitox treatment, you may become infected with the virus or bacteria from the vaccine. Also, live vaccines may be less effective in people receiving denileukin diftitox. Talk to your healthcare provider before receiving a vaccination while you are undergoing this chemotherapy treatment.
Sipuleucel-T may be less effective if combined with denileukin diftitox. Talk to your healthcare provider about this possible interaction before using these drugs together.
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Denileukin Diftitox Drug Information

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