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Dacarbazine Side Effects

Some of the possible side effects of dacarbazine can include loss of appetite, vomiting, and hair loss. This prescription chemotherapy drug can also cause significant problems, such as serious infections, allergic reactions, and anemia, which require medical treatment right away. Let your healthcare provider know if you experience anything that doesn't seem right during dacarbazine treatment.

An Introduction to Side Effects of Dacarbazine

As with other chemotherapy medicines, dacarbazine (DTIC-Dome®) can cause side effects, some of which can be significant. In fact, the majority of people using this medicine will experience some type of reaction during treatment. Talk to your healthcare provider about ways to prevent or lessen reactions to this medicine.
(This article covers many, but not all, of the possible side effects with dacarbazine. Your healthcare provider can discuss a more complete list with you.)

Serious Dacarbazine Side Effects

Some side effects of dacarbazine are potentially serious and should be reported immediately to your healthcare provider. These include but are not limited to:
  • Signs of an allergic reaction, such as:
    • An unexplained rash
    • Hives
    • Itching
    • Unexplained swelling, especially of the mouth, lips, or throat
    • Wheezing
    • Difficulty breathing or swallowing
  • Signs of infection, such as:
    • Fever
    • Chills
    • Aches and pains
    • A sore throat
    • Shortness of breath
    • Cough
  • Signs of anemia, such as:
    • Extreme weakness or fatigue
    • Pale skin
    • Shortness of breath
    • Dizziness
  • Unusual bleeding or bruising
  • Black, tarry stools or stool with blood in it
  • Signs of liver problems, such as:
    • Yellowing of the skin or whites of the eyes (jaundice)
    • Dark urine
    • Pale stool
    • Upper-right abdominal (stomach) pain
  • Persistent or extreme nausea and vomiting
  • Pain, redness, swelling, or irritation at your IV site (the site where you receive your injection).
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